The Hidden Dangers of Synthetic Citric Acid: How It Affects Your Body & Fuels Mold Growth
- naturella134
- Mar 13
- 12 min read

Introduction: What Is Synthetic Citric Acid?
Citric acid is a common food additive found in countless processed foods, beverages, and personal care products. While many believe it comes from citrus fruits like lemons and oranges, the truth is that most commercial citric acid is synthetically derived from black mold (Aspergillus niger). This synthetic version, known as manufactured or industrial citric acid (MCA), is mass-produced in a lab using fermented GMO corn and sugar, making it far different from the naturally occurring citric acid found in fruits.
Although citric acid is labeled as "natural" on many products, its synthetic production raises concerns about its potential health risks, effects on mold growth in the body, and impact on metabolic health.
How Synthetic Citric Acid Is Made & Used in Products
How Is It Manufactured?
Most commercially produced citric acid is not derived from citrus fruits but is instead manufactured using a process that involves Aspergillus niger, a type of black mold.
How It’s Made:
Fermentation Process – Aspergillus niger is fed a sugar source (usually from corn or sugar beets, often GMO).
Citric Acid Production – The mold metabolizes the sugar and produces citric acid as a byproduct.
Extraction & Purification – The citric acid is then filtered, purified, and crystallized for commercial use.
This method is used because it's far cheaper and more efficient than extracting citric acid from lemons, limes, or other citrus fruits. While the final product is purified and should not contain active mold, some people are sensitive to residual mold metabolites or react negatively to citric acid derived from this process.
Where Do You Find Synthetic Citric Acid?
Synthetic citric acid (produced from black mold fermentation) is used in a wide range of industries, including food, beverages, cosmetics, pharmaceuticals, and industrial products. Here’s where you’ll commonly find it:
1. Food & Beverages
Preservative – Extends shelf life in packaged foods.
Flavor Enhancer – Adds a tart, citrus-like taste to sodas, candies, and processed foods.
Acidulant – Regulates acidity in jams, jellies, and canned goods.
Emulsifier – Prevents fats from separating in dairy products like ice cream.
2. Pharmaceuticals & Supplements
Tablet Formulation – Helps tablets dissolve quickly (like effervescent vitamin C).
Preservative – Used in liquid medications and syrups.
Chelating Agent – Binds metals in supplements and medications to improve absorption.
3. Personal Care & Cosmetics
pH Adjuster – Found in shampoos, soaps, and skincare products.
Preservative – Extends shelf life in creams and lotions.
Exfoliant – Used in some facial peels and anti-aging products.
4. Cleaning Products
Descaler – Helps remove limescale and mineral deposits in dishwashing and laundry detergents.
Natural Cleaner – Used in eco-friendly household cleaning products.
Rust Remover – Found in metal cleaning solutions.
5. Industrial & Agricultural Uses
Textile Industry – Used in dyeing and fabric softening.
Agriculture – Acts as a preservative in animal feed.
Water Treatment – Used to chelate metals and purify water.
Hidden Sources: You’ll find synthetic citric acid in almost every processed food and drink, from soft drinks to packaged snacks, frozen meals, and even baby food!
Health Implications of Ingesting Synthetic Citric Acid
While citric acid occurs naturally in citrus fruits, the synthetic version (produced from Aspergillus niger, a black mold) can have different effects on the body, particularly in individuals who are sensitive to mold-derived compounds or those with underlying health issues.
1. Potential Accumulation in the Body
Chelating Properties: Citric acid binds with minerals such as calcium, magnesium, and iron. Over time, excessive intake may lead to mineral depletion, particularly if the diet is already deficient in these nutrients.
Inflammatory Response: Some people may experience chronic low-grade inflammation due to mold metabolites or other residual byproducts in synthetic citric acid.
Cellular Damage: Studies suggest that excessive citric acid intake can contribute to oxidative stress, potentially damaging tissues and DNA.
2. Effects on the Kidneys
Kidney Stones: Citric acid can both prevent and contribute to kidney stones, depending on the type and source.
Natural citric acid (from citrus fruits) can help prevent kidney stones by binding with calcium and reducing stone formation.
Synthetic citric acid, however, may contribute to stone formation by binding minerals in ways that promote crystallization, especially in people prone to calcium oxalate stones.
Renal Stress: People with kidney disease or impaired kidney function may struggle to process high amounts of citric acid, leading to electrolyte imbalances and potential kidney strain.
Increased Acidity: Excessive citric acid intake may contribute to metabolic acidosis, a condition where the body becomes overly acidic, forcing the kidneys to work harder to maintain pH balance.
3. Gut & Digestive Issues
Irritation of the GI Tract: Citric acid can erode the gut lining, leading to acid reflux, heartburn, and gastritis in sensitive individuals.
Microbiome Disruption: Since synthetic citric acid is mold-derived, some people experience gut flora imbalances, potentially leading to leaky gut syndrome or food sensitivities.
4. Immune System & Allergic Reactions
Mold Sensitivity & Histamine Response: Some individuals, especially those with mold allergies, may react negatively to synthetic citric acid, experiencing skin rashes, headaches, fatigue, joint pain, and brain fog.
Inflammatory Conditions: People with autoimmune disorders (such as lupus, fibromyalgia, or rheumatoid arthritis) may find that synthetic citric acid worsens inflammation and flare-ups.
Should You Avoid Synthetic Citric Acid?
If you experience digestive issues, kidney problems, inflammation, or mold sensitivity, reducing or eliminating synthetic citric acid from your diet may help reduce symptoms and improve overall well-being.
The Connection Between Synthetic Citric Acid & Mold Overgrowth in the Body
One of the biggest concerns with synthetic citric acid is its role in fueling mold and mildew growth inside the body. Since it is produced using Aspergillus niger (a type of mold), it may create an internal environment that encourages fungal overgrowth, particularly in those with compromised immune systems or gut imbalances.
How Citric Acid Supports Mold & Mildew in the Body
Disrupts Gut Flora – Mold-derived citric acid can weaken beneficial gut bacteria, allowing Candida and other fungi to thrive.
Feeds Pathogenic Yeast – Since citric acid is often derived from sugar, it may indirectly fuel yeast infections and Candida overgrowth.
Lowers pH Balance – An overly acidic body environment encourages fungal infections, chronic fatigue, and immune suppression.
Symptoms of Mold & Fungal Overgrowth
If you regularly consume synthetic citric acid, you may experience:
Chronic fatigue & brain fog
Persistent sinus infections & allergies
Skin conditions like eczema or acne
Digestive issues & bloating
Recurring yeast infections or Candida overgrowth
These symptoms may worsen over time, especially if combined with a diet high in processed foods, sugars, and other mold-contaminated products like peanuts, coffee, or grains.
What is Considered Excessive Citric Acid Consumption?
The definition of excessive citric acid intake depends on factors such as diet, kidney function, metabolic health, and individual sensitivity to synthetic citric acid. While there is no universally established upper limit for daily consumption, we can assess excessive intake based on the following factors:
1. General Intake Guidelines
Natural citric acid (from fruits) is generally safe, with lemons and limes containing 1-8 grams per fruit.
Synthetic citric acid (found in processed foods) is often consumed in much higher amounts, sometimes multiple grams per day in the average diet.
Excessive intake is typically defined as:
Over 4–6 grams per day from processed foods and beverages (common in people consuming lots of sodas, energy drinks, and packaged foods).
Frequent consumption of multiple citric acid-containing products daily (e.g., sodas, canned foods, flavored waters, and supplements).
Citric acid additives in non-food products (such as cosmetics, medications, and cleaning products) that contribute to overall exposure.
2. Signs of Excessive Citric Acid Intake
Digestive Discomfort: Acid reflux, heartburn, bloating, or diarrhea.
Tooth Erosion: Citric acid can weaken enamel over time, leading to sensitivity and cavities.
Kidney Strain: Increased risk of kidney stones, mineral imbalances, or metabolic acidosis.
Inflammation & Joint Pain: Some individuals report worsened arthritis or autoimmune symptoms.
Histamine Reactions: Skin rashes, headaches, fatigue, or allergy-like symptoms, especially in people sensitive to mold-derived compounds.
3. High-Risk Populations for Excessive Intake
Certain individuals may experience negative effects at lower intake levels, including:
People with kidney disease or kidney stone history (synthetic citric acid can contribute to stone formation).
Those with digestive disorders (acid reflux, gastritis, IBS, or leaky gut).
Individuals with mold allergies or chemical sensitivities (can trigger inflammatory responses).
People consuming high amounts of processed foods daily (sodas, candy, canned goods, supplements, etc.).
How to Reduce Excessive Citric Acid Intake
Read ingredient labels – Avoid foods with "citric acid" as an additive.
Choose fresh, whole foods – Stick to natural sources of citric acid (lemons, limes, oranges).
Limit processed beverages – Reduce sodas, flavored waters, and packaged juices.
Monitor symptoms – If you experience digestive issues, fatigue, or inflammation, consider an elimination test to see if synthetic citric acid is a trigger.
DID YOU KNOW? Citric acid can be hidden under different names on ingredient labels, especially in processed foods, personal care products, and pharmaceuticals. Here are some hidden names and alternative terms to watch for:
1. Common Alternative Names for Citric Acid
2-Hydroxy-1,2,3-propane-tricarboxylic acid (scientific name)
Sodium citrate (a salt form of citric acid)
Potassium citrate (another salt form, often in supplements)
Calcium citrate (found in fortified foods and supplements)
Magnesium citrate (used as a laxative and supplement)
Trisodium citrate (common in processed foods as a preservative)
2. Hidden Sources in Food Labels
Many processed foods contain citric acid under different descriptions:
Natural flavors (sometimes contains citric acid derivatives)
Acidulant (a generic term for acidity regulators)
Preservative E330 (European food additive code for citric acid)
Sour salt (sometimes used in processed foods as a flavor enhancer)
3. Hidden Sources in Personal Care Products
Citric acid is often disguised in beauty and hygiene products:
pH Adjuster (used in shampoos, skincare, and soaps)
Chelating Agent (binds metals in water-based cosmetics)
AHA (Alpha Hydroxy Acid) (used in exfoliating products)
4. Hidden Names in Pharmaceuticals & Supplements
Buffering Agent (helps stabilize drug formulations)
Effervescent Agent (used in dissolvable tablets like vitamin C)
Flavor Enhancer (found in syrups, chewable tablets, and powders)
Citric Acid Contribute to Allergies
Synthetic citric acid (manufactured from Aspergillus niger, a black mold) can trigger allergic reactions and inflammatory responses in certain individuals, especially those with mold sensitivities, histamine intolerance, autoimmune conditions, or a weakened immune system.
1. How Citric Acid Triggers Allergic Reactions
Unlike natural citric acid found in fruits, synthetic citric acid may contain residual mold toxins, fermentation byproducts, and chemical contaminants that can irritate the immune system. Here’s how:
Histamine Release – Citric acid can act as a histamine liberator, potentially worsening symptoms for those with histamine intolerance or mast cell activation syndrome (MCAS).
Immune System Activation – Some individuals experience autoimmune flares, skin rashes, or joint pain due to immune reactivity to mold-based byproducts.
Gut Disruption – Citric acid may alter gut bacteria and contribute to leaky gut syndrome, leading to food sensitivities and chronic inflammation.
2. Common Allergy Symptoms Linked to Synthetic Citric Acid
Skin Issues – Rashes, hives, eczema, itching, and swelling
Respiratory Problems – Sinus congestion, sneezing, wheezing, or asthma-like symptoms
Digestive Distress – Acid reflux, bloating, nausea, or diarrhea
Joint & Muscle Pain – Inflammation, stiffness, or autoimmune-like flare-ups
Neurological Symptoms – Headaches, brain fog, dizziness, fatigue, or anxiety
3. Who Is Most at Risk?
People with mold allergies – May react to mold-derived metabolites.
Individuals with histamine intolerance or MCAS – Citric acid can worsen histamine overload.
Those with autoimmune conditions – Synthetic citric acid may contribute to immune flare-ups.
People with sensitive skin – Found in many skincare products, causing irritation.
Those with gut health issues – Can contribute to dysbiosis, bloating, or acid reflux.
4. How to Avoid Citric Acid Allergies
Read labels carefully – Avoid processed foods, drinks, and supplements with “citric acid” listed.
Choose natural alternatives – Use fresh lemon/lime juice instead of citric acid additives.
Test for sensitivities – If you suspect a reaction, try eliminating citric acid for a few weeks and monitor symptoms.
Opt for clean skincare – Look for citric acid-free personal care products.
How to Avoid Synthetic Citric Acid & Protect Your Health
1. Read Labels Carefully
Look for "citric acid" on ingredient lists—it is often hidden in many processed foods. If possible, choose products labeled "naturally derived" or "fruit-derived" citric acid.
2. Choose Fresh, Whole Foods
Instead of processed products, eat fresh fruits, vegetables, and homemade meals.
Use natural acids like lemon juice or apple cider vinegar as food preservatives.
3. Support Gut & Detox Pathways
Take probiotics to maintain healthy gut flora and combat fungal overgrowth.
Use binders like activated charcoal or bentonite clay to help remove toxins.
Drink herbal teas like Pau d’Arco, burdock root, and ginger to support detoxification
.4. Reduce Mold Exposure.
Avoid foods that commonly contain hidden mold, like peanuts, corn, soy, and aged cheeses.
Keep indoor spaces dry, well-ventilated, and free from mold buildup.
How Natural Citric Acid (from Citrus Fruits) Works in the Body
Supports Alkalinity & pH Balance – Although citric acid is acidic outside the body, once metabolized, it helps create an alkaline environment, supporting pH balance.
Enhances Mineral Absorption – Helps the body absorb key minerals like magnesium, calcium, and potassium, improving bone health and muscle function.
Aids Detoxification – Natural citric acid binds to heavy metals (like lead and aluminum) and helps remove them from the body.
Supports Digestion & Liver Function – Stimulates bile production, improving fat digestion and liver detox.
Protects Against Kidney Stones – Increases urinary citrate levels, which helps prevent the formation of calcium oxalate kidney stones.
Rich in Antioxidants & Bioflavonoids – Citrus fruits provide vitamin C and plant compounds that reduce inflammation and boost immunity.
Found in: Lemons, limes, oranges, grapefruits, pineapples, strawberries
How Synthetic Citric Acid (from Black Mold) Works in the Body
Can Contribute to Inflammation & Immune Reactions – Because it is derived from Aspergillus niger (a black mold), some individuals may react to residual mold toxins or fermentation byproducts.
May Strip Essential Minerals – Synthetic citric acid acts as a chelating agent, but instead of nourishing the body, it can bind to beneficial minerals like calcium and magnesium, leading to potential mineral depletion over time.
May Disrupt Gut Health – Some people report acid reflux, bloating, or gut irritation, possibly due to its effect on stomach acid levels and gut microbiota.
Can Worsen Histamine Sensitivity – Synthetic citric acid can act as a histamine liberator, triggering reactions in those with Mast Cell Activation Syndrome (MCAS) or histamine intolerance.
May Contribute to Kidney Stress – Unlike natural citric acid, which helps prevent kidney stones, synthetic citric acid may increase kidney stone risk in susceptible individuals due to its chelating effects on minerals.
Identifying Products with Synthetic Citric Acid:
To minimize consumption of synthetic citric acid:
Read Ingredient Labels Carefully: Citric acid is commonly listed as an ingredient in processed foods, beverages, and personal care products.
Seek Clarification from Manufacturers: If the source of citric acid is not specified, consider reaching out to the manufacturer for more information.
Choose Certified Organic Products: Organic certifications often have stricter guidelines regarding additives and their sources.
Key Differences in How They Work in the Body
Feature | Natural Citric Acid (Fruits) | Synthetic Citric Acid (Black Mold) |
Source | Lemons, limes, oranges, berries | Aspergillus niger (black mold) |
Supports pH Balance? | Yes, helps alkalize the body | No, may disrupt mineral balance |
Affects Mineral Absorption? | Enhances calcium, magnesium, potassium absorption | May deplete essential minerals |
Kidney Health | Helps prevent kidney stones | May contribute to kidney stone formation |
Gut Health | Supports digestion and gut flora | May cause irritation or inflammation |
Histamine & Allergies | Generally well-tolerated | Can trigger histamine reactions |
Detox Benefits | Helps eliminate heavy metals naturally | May introduce mold residues or toxins |
Inflammation Risk | Anti-inflammatory & antioxidant-rich | May cause immune reactions in sensitive individuals |
Your Health Starts with Awareness!
While citric acid is widely used as a preservative and flavor enhancer, its synthetic production methods raise concerns for some consumers. Being vigilant about ingredient sources and choosing products that align with personal health preferences can help mitigate potential risks associated with synthetic additives.
Final Thoughts on Citric Acid & Protecting Yourself from Toxic Mold Exposure
While natural citric acid from fruits supports digestion, detoxification, and mineral absorption, synthetic citric acid (manufactured from black mold fermentation) poses potential health risks, including inflammation, mineral depletion, gut irritation, kidney stress, and allergic reactions. Many processed foods, supplements, and personal care products contain hidden synthetic citric acid, making it a common but often overlooked source of mold exposure.
To protect yourself from toxic mold exposure and synthetic citric acid, follow these guidelines:
1. Read Labels & Avoid Processed Foods
Check ingredient lists for "citric acid"—if it’s not from citrus fruit, it’s likely synthetic
Avoid canned goods, sodas, candy, and prepackaged foods that often contain synthetic citric acid as a preservative.
Be cautious of "natural flavors" or E330 (European food additive code for citric acid) in processed products.
2. Choose Whole, Fresh, & Organic Foods
Get citric acid naturally from lemons, limes, oranges, and berries instead of processed foods.
Opt for fresh or frozen fruits and vegetables instead of canned or prepackaged options.
Select organic products whenever possible, as they are less likely to contain synthetic citric acid or GMO-derived ingredients.
3. Be Mindful of Supplements & Medications
Many vitamins, protein powders, and effervescent tablets contain synthetic citric acid as a binder or preservative.
Look for "citric acid-free" options in supplements, or choose those derived from whole-food sources
If necessary, contact supplement manufacturers to confirm the source of citric acid.
4. Avoid Personal Care Products with Citric Acid
Skincare products, shampoos, lotions, and even toothpaste often contain synthetic citric acid as a pH adjuster or preservative.
Choose organic, clean beauty products with natural pH balancers like aloe vera or apple cider vinegar.
5. Detox & Support Your Body
Stay Hydrated – Drink filtered water with fresh lemon to support natural detox pathways.
Detox with Binders – Use bentonite clay, activated charcoal, chlorella, or zeolite to help remove mold toxins from the body.
Support the Liver – Drink Natural SOULutions Pure Cleanse Tea and Tincture Blends to aid liver detoxification.
Eat Anti-Inflammatory Foods – Consume leafy greens, turmeric, and cruciferous vegetables to counteract inflammation.
6. Test for Mold Sensitivity & Address Health Issues
If you suspect mold toxicity or histamine intolerance, consider functional medicine testing for:
Mold exposure (Mycotoxin testing)
Histamine levels & Mast Cell Activation Syndrome (MCAS)
Mineral deficiencies (Calcium, Magnesium, Potassium, etc.)
Final Takeaway
Avoiding synthetic citric acid is a simple but effective step in reducing toxic mold exposure, preventing mineral depletion, and lowering inflammation. By choosing whole foods, clean supplements, and natural personal care products, you can protect your body from unnecessary toxins and support long-term health.
Next time you pick up a product containing citric acid, ask yourself: Is this coming from a real lemon, or is it a hidden byproduct of black mold? Your body will thank you for making cleaner, healthier choices!